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  <xs:element name="WaiverofLoanGrantedtoSubsidiary" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_WaiverofLoanGrantedtoSubsidiary"/>
  <xs:element name="ChangesInFairValueOfInvestments" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ChangesInFairValueOfInvestments"/>
  <xs:element name="GainOnAmountsFundedInRespectOfEmployeeRightsUponRetirement" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_GainOnAmountsFundedInRespectOfEmployeeRightsUponRetirement"/>
  <xs:element name="ChangeInAccruedInterestOnShorttermBorrowings" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ChangeInAccruedInterestOnShorttermBorrowings"/>
  <xs:element name="IncreaseDecreaseinDeferredIncome" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_IncreaseDecreaseinDeferredIncome"/>
  <xs:element name="ProceedsFromInvestmentAtFairValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ProceedsFromInvestmentAtFairValue"/>
  <xs:element name="ExerciseOfClosingPennyWarrantsAndSubsequentPennyWarrants" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ExerciseOfClosingPennyWarrantsAndSubsequentPennyWarrants"/>
  <xs:element name="PaymentToEquityMethodInvestee" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_PaymentToEquityMethodInvestee"/>
  <xs:element name="InterestReceived" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_InterestReceived"/>
  <xs:element name="TwoThousandTwentyFourRefinancingTrancheA" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_TwoThousandTwentyFourRefinancingTrancheA"/>
  <xs:element name="TwoThousandTwentyFourRefinancingTrancheB" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_TwoThousandTwentyFourRefinancingTrancheB"/>
  <xs:element name="ExciseTaxForRepurchaseAndRetirementOfCommonStock" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ExciseTaxForRepurchaseAndRetirementOfCommonStock"/>
  <xs:element name="RecognitionOfOperatingLeaseRightofuseAssetsAndLiabilities" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_RecognitionOfOperatingLeaseRightofuseAssetsAndLiabilities"/>
  <xs:element name="WaiverOfLoanGrantedToSubsidiary" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_WaiverOfLoanGrantedToSubsidiary"/>
  <xs:element name="DerecognitionOfRightofuseAsset" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_DerecognitionOfRightofuseAsset"/>
  <xs:element name="DerecognitionOfLeaseLiability" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_DerecognitionOfLeaseLiability"/>
  <xs:element name="PurchasesOfMarketableSecuritiesNotYetSettled" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_PurchasesOfMarketableSecuritiesNotYetSettled"/>
  <xs:element name="DividendsDeclaredButNotYetPaidInCash" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_DividendsDeclaredButNotYetPaidInCash"/>
  <xs:element name="WarrantsReceivedFromAlphaTau" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_WarrantsReceivedFromAlphaTau"/>
  <xs:element name="ShortTermDepositsTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ShortTermDepositsTextBlock"/>
  <xs:element name="ConvertibleSecuredPromissoryNoteTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ConvertibleSecuredPromissoryNoteTextBlock"/>
  <xs:element name="OtherNonMarketableEquitySecuritiesDisclosureTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_OtherNonMarketableEquitySecuritiesDisclosureTextBlock"/>
  <xs:element name="GeneralAccountingPoliciesPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_GeneralAccountingPoliciesPolicyTextBlock"/>
  <xs:element name="RepurchaseAndRetirementOfCommonStockPolicyPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RepurchaseAndRetirementOfCommonStockPolicyPolicyTextBlock"/>
  <xs:element name="OtherNonmarketableEquitySecuritiesPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_OtherNonmarketableEquitySecuritiesPolicyTextBlock"/>
  <xs:element name="OtherIncomePolicyPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_OtherIncomePolicyPolicyTextBlock"/>
  <xs:element name="InvestmentInAlphaTauPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_InvestmentInAlphaTauPolicyTextBlock"/>
  <xs:element name="ScheduleOfShortTermDepositsTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScheduleOfShortTermDepositsTableTextBlock"/>
  <xs:element name="ScheduleOfAssumptionsAndEstimatesValuationTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScheduleOfAssumptionsAndEstimatesValuationTableTextBlock"/>
  <xs:element name="ScheduleOfRefinancingTransactionTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScheduleOfRefinancingTransactionTableTextBlock"/>
  <xs:element name="ScheduleOfSecuredPromissoryNoteAssumptionsAndEstimatesThatUsedForTheValuationTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScheduleOfSecuredPromissoryNoteAssumptionsAndEstimatesThatUsedForTheValuationTableTextBlock"/>
  <xs:element name="InformationByCategoryOfDebtSecurityDomainDomain" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_InformationByCategoryOfDebtSecurityDomainDomain"/>
  <xs:element name="ShortTermDepositsScheduleofShortTermDepositsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_ShortTermDepositsScheduleofShortTermDepositsDetailsTable"/>
  <xs:element name="InvestmentsatFairValueScheduleofFairValueCompositionDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_InvestmentsatFairValueScheduleofFairValueCompositionDetailsTable"/>
  <xs:element name="InvestmentsatFairValueScheduleofAssumptionsandEstimatesValuationDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_InvestmentsatFairValueScheduleofAssumptionsandEstimatesValuationDetailsTable"/>
  <xs:element name="InvestmentsatFairValueScheduleofAssumptionsandEstimatesValuationDetailsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_InvestmentsatFairValueScheduleofAssumptionsandEstimatesValuationDetailsLineItems"/>
  <xs:element name="InvestmentsatFairValueScheduleofRefinancingTransactionDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_InvestmentsatFairValueScheduleofRefinancingTransactionDetailsTable"/>
  <xs:element name="ScilexTransaction" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScilexTransaction"/>
  <xs:element name="ProceedsFromTheSaleOfTransferredWarrants" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ProceedsFromTheSaleOfTransferredWarrants"/>
  <xs:element name="ReclassificationOfExercisedWarrants" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ReclassificationOfExercisedWarrants"/>
  <xs:element name="IncomeFromTheRoyaltyAgreement" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_IncomeFromTheRoyaltyAgreement"/>
  <xs:element name="PrincipalPayments" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_PrincipalPayments"/>
  <xs:element name="ProceedsFromTheSaleOfSubsequentPennyWarrants" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ProceedsFromTheSaleOfSubsequentPennyWarrants"/>
  <xs:element name="InterestPayments" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_InterestPayments"/>
  <xs:element name="AccruedInterest" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_AccruedInterest"/>
  <xs:element name="LoanAgreementMeasuredinFairValueScheduleofFairValueBreakdownDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_LoanAgreementMeasuredinFairValueScheduleofFairValueBreakdownDetailsTable"/>
  <xs:element name="ConvertibleSecuredPromissoryNoteScheduleofAssumptionsandEstimatesthatWereUsedfortheValuationDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_ConvertibleSecuredPromissoryNoteScheduleofAssumptionsandEstimatesthatWereUsedfortheValuationDetailsTable"/>
  <xs:element name="MaturityDatedDescription" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_MaturityDatedDescription"/>
  <xs:element name="StockBasedCompensationScheduleofStockOptionsGrantedtoEmployeesandDirectorsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_StockBasedCompensationScheduleofStockOptionsGrantedtoEmployeesandDirectorsDetailsTable"/>
  <xs:element name="StockBasedCompensationScheduleofConcerningtheOptionsGrantedtoNonEmployeesOutstandingDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_StockBasedCompensationScheduleofConcerningtheOptionsGrantedtoNonEmployeesOutstandingDetailsTable"/>
  <xs:element name="StockBasedCompensationScheduleofUnvestedRSUsandPSUsGrantedtoEmployeesandDirectorsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_StockBasedCompensationScheduleofUnvestedRSUsandPSUsGrantedtoEmployeesandDirectorsDetailsTable"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsIssuedInPeriod" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsIssuedInPeriod"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsExpiredInPeriod" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsExpiredInPeriod"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndUnissuedInPeriod" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndUnissuedInPeriod"/>
  <xs:element name="AdjustmentForDividendsAttributableToUnvestedRSUBasic" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_AdjustmentForDividendsAttributableToUnvestedRSUBasic"/>
  <xs:element name="AdjustmentForDividendsAttributableToUnvestedRSUDiluted" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_AdjustmentForDividendsAttributableToUnvestedRSUDiluted"/>
  <xs:element name="FinancialIncomeLossNetScheduleofFinancialIncomeLossNetDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_FinancialIncomeLossNetScheduleofFinancialIncomeLossNetDetailsTable"/>
  <xs:element name="FinancialIncomeLossNetScheduleofFinancialIncomeLossNetDetailsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_FinancialIncomeLossNetScheduleofFinancialIncomeLossNetDetailsLineItems"/>
  <xs:element name="FinancialIncomeLossNet" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_FinancialIncomeLossNet"/>
  <xs:element name="DeferredTaxAssetsIRevaluationOfInvestments" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_DeferredTaxAssetsIRevaluationOfInvestments"/>
  <xs:element name="TaxesonIncomeScheduleofIncomeLossBeforeTaxesonIncomeDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_TaxesonIncomeScheduleofIncomeLossBeforeTaxesonIncomeDetailsTable"/>
  <xs:element name="TaxesonIncomeScheduleofIncomeLossBeforeTaxesonIncomeDetailsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TaxesonIncomeScheduleofIncomeLossBeforeTaxesonIncomeDetailsLineItems"/>
  <xs:element name="IncomeLossFromContinuingOperationsBeforePriorYearTaxes" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_IncomeLossFromContinuingOperationsBeforePriorYearTaxes"/>
  <xs:element name="EffectiveIncomeTaxUncertainTaxPosition" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_EffectiveIncomeTaxUncertainTaxPosition"/>
  <xs:element name="SharebasedPaymentAwardsValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_SharebasedPaymentAwardsValue"/>
  <xs:element name="EffectiveIncomeTaxRateSharebasedPaymentAwardsPercenatge" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_EffectiveIncomeTaxRateSharebasedPaymentAwardsPercenatge"/>
  <xs:element name="EffectiveIncomeTaxRatChangeInValuationAllowanceValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_EffectiveIncomeTaxRatChangeInValuationAllowanceValue"/>
  <xs:element name="EffectiveIncomeTaxRateChangeInTheValuationAllowancePercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_EffectiveIncomeTaxRateChangeInTheValuationAllowancePercentage"/>
  <xs:element name="StatutoryTaxbenefitExpenseAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_StatutoryTaxbenefitExpenseAmount"/>
  <xs:element name="StatutoryTaxbenefitExpensePercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_StatutoryTaxbenefitExpensePercentage"/>
  <xs:element name="EffectiveIncomeTaxRateReconciliationsCrossborderTaxLawsPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_EffectiveIncomeTaxRateReconciliationsCrossborderTaxLawsPercentage"/>
  <xs:element name="SignificantAccountingPoliciesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_SignificantAccountingPoliciesDetailsTable"/>
  <xs:element name="PercentageOfIssuedAndOutstandingShareCapital" type="dtr:percentItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfIssuedAndOutstandingShareCapital"/>
  <xs:element name="AggregatePurchasePrice" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_AggregatePurchasePrice"/>
  <xs:element name="LiabilityIsExpected" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_LiabilityIsExpected"/>
  <xs:element name="AggregateAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_AggregateAmount"/>
  <xs:element name="StraightlineIncomeRecognition" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_StraightlineIncomeRecognition"/>
  <xs:element name="MarketableSecuritiesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_MarketableSecuritiesDetailsTable"/>
  <xs:element name="GrossProceeds" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_GrossProceeds"/>
  <xs:element name="PercentageOfTransactionFees" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfTransactionFees"/>
  <xs:element name="AgreementDomainDomain" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AgreementDomainDomain"/>
  <xs:element name="InvestmentsatFairValueDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_InvestmentsatFairValueDetailsTable"/>
  <xs:element name="ExercisableWarrants" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ExercisableWarrants"/>
  <xs:element name="ExchangeForShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ExchangeForShares"/>
  <xs:element name="RefinancedAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_RefinancedAmount"/>
  <xs:element name="PrincipalOutstandingBalance" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_PrincipalOutstandingBalance"/>
  <xs:element name="SharesOfCommonStock" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_SharesOfCommonStock"/>
  <xs:element name="WarrantsToPurchaseShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_WarrantsToPurchaseShares"/>
  <xs:element name="AggregatePrincipalAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_AggregatePrincipalAmount"/>
  <xs:element name="RepayableQuarterlyBasisPeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RepayableQuarterlyBasisPeriod"/>
  <xs:element name="PercentageOfTranchePurchased" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfTranchePurchased"/>
  <xs:element name="TrancheBWarrant" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TrancheBWarrant"/>
  <xs:element name="PercentageOfNetSales" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfNetSales"/>
  <xs:element name="NetSalesWorldwidePeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NetSalesWorldwidePeriod"/>
  <xs:element name="PercentageOfPurchasedReceivables" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfPurchasedReceivables"/>
  <xs:element name="PercentageOfRightToReceiveRoyalties" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfRightToReceiveRoyalties"/>
  <xs:element name="PrincipalAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_PrincipalAmount"/>
  <xs:element name="TermOfNetSales" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TermOfNetSales"/>
  <xs:element name="PecentageOfCashPurchasePrice" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PecentageOfCashPurchasePrice"/>
  <xs:element name="PercentageOfDiscountRate" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfDiscountRate"/>
  <xs:element name="PercentageOfBeneficialOwnership" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfBeneficialOwnership"/>
  <xs:element name="PercentageOfProjectProfits" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfProjectProfits"/>
  <xs:element name="EquityMethodInvesteeDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_EquityMethodInvesteeDetailsTable"/>
  <xs:element name="PercentageOfIssuedAndOutstandingCapitalStock" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfIssuedAndOutstandingCapitalStock"/>
  <xs:element name="AcquiredRightsPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AcquiredRightsPercentage"/>
  <xs:element name="NetProfitsPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NetProfitsPercentage"/>
  <xs:element name="AdditionalSharesToWarrantsPurchase" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AdditionalSharesToWarrantsPurchase"/>
  <xs:element name="AcquiredSharesOfCommonStock" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AcquiredSharesOfCommonStock"/>
  <xs:element name="NumberOfRoyaltyVestSold" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_NumberOfRoyaltyVestSold"/>
  <xs:element name="RoyaltyVestContinuesToHold" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_RoyaltyVestContinuesToHold"/>
  <xs:element name="LoanAgreementMeasuredinFairValueDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_LoanAgreementMeasuredinFairValueDetailsTable"/>
  <xs:element name="PercentageOfWeightedAverageCashflowsOfLoanDiscounted" type="dtr:percentItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfWeightedAverageCashflowsOfLoanDiscounted"/>
  <xs:element name="InvestmentinAssociateatFairValueDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_InvestmentinAssociateatFairValueDetailsTable"/>
  <xs:element name="PercentageOfOrdinaryShares" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfOrdinaryShares"/>
  <xs:element name="NonRefundableFee" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_NonRefundableFee"/>
  <xs:element name="PercentageOfVotingInterest" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfVotingInterest"/>
  <xs:element name="ConvertibleSecuredPromissoryNoteDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_ConvertibleSecuredPromissoryNoteDetailsTable"/>
  <xs:element name="SecuredPromissoryNoteBearingInterestRate" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_SecuredPromissoryNoteBearingInterestRate"/>
  <xs:element name="SecuredPromissoryNoteMaturityDate" type="xbrli:dateItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_SecuredPromissoryNoteMaturityDate"/>
  <xs:element name="OrdinarySharesConversionPrice" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_OrdinarySharesConversionPrice"/>
  <xs:element name="AdjustedConversionPrice" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AdjustedConversionPrice"/>
  <xs:element name="PercentageOfSharesHoldOfIssuedAndOutstanding" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfSharesHoldOfIssuedAndOutstanding"/>
  <xs:element name="ChangeInTheValueOfInvestment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ChangeInTheValueOfInvestment"/>
  <xs:element name="AccountsPayableandAccruedExpensesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_AccountsPayableandAccruedExpensesDetailsTable"/>
  <xs:element name="AccountsPayableandAccruedExpensesDetailsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AccountsPayableandAccruedExpensesDetailsLineItems"/>
  <xs:element name="ShortTermBorrowingsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_ShortTermBorrowingsDetailsTable"/>
  <xs:element name="CommitmentsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_CommitmentsDetailsTable"/>
  <xs:element name="AgreementTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_AgreementTerm"/>
  <xs:element name="TerminationTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_TerminationTerm"/>
  <xs:element name="SalesBasedRoyaltiesPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_SalesBasedRoyaltiesPercentage"/>
  <xs:element name="RoyaltiesPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_RoyaltiesPercentage"/>
  <xs:element name="StockholdersEquityDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_StockholdersEquityDetailsTable"/>
  <xs:element name="AggregateOfferingPrice" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_AggregateOfferingPrice"/>
  <xs:element name="PercentageOfCommission" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfCommission"/>
  <xs:element name="AveragePriceOfPerShare" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AveragePriceOfPerShare"/>
  <xs:element name="PurchasePriceOfPerShare" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PurchasePriceOfPerShare"/>
  <xs:element name="StockBasedCompensationDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_StockBasedCompensationDetailsTable"/>
  <xs:element name="NumberOfOptionsExercisable" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_NumberOfOptionsExercisable"/>
  <xs:element name="NumberOfQuarterlyInstallments" type="xbrli:integerItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NumberOfQuarterlyInstallments"/>
  <xs:element name="NumberOfAnnualInstallments" type="xbrli:integerItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NumberOfAnnualInstallments"/>
  <xs:element name="NumberOfInstallment" type="xbrli:integerItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NumberOfInstallment"/>
  <xs:element name="ShareBasedPaymentArrangementUnrecognizedCompensationCostsExpectedWeightedAveragePeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ShareBasedPaymentArrangementUnrecognizedCompensationCostsExpectedWeightedAveragePeriod"/>
  <xs:element name="TaxesonIncomeDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_TaxesonIncomeDetailsTable"/>
  <xs:element name="CorporateTaxationTerm" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_CorporateTaxationTerm"/>
  <xs:element name="UnrecognizedTaxExpensesTerms" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_UnrecognizedTaxExpensesTerms"/>
  <xs:element name="RelatedPartyTransactionsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_RelatedPartyTransactionsDetailsTable"/>
  <xs:element name="ConsultingFee" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_ConsultingFee"/>
  <xs:element name="SubsequentEventsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="ormp_SubsequentEventsDetailsTable"/>
  <xs:element name="PurchasedAnAdditionalShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_PurchasedAnAdditionalShares"/>
  <xs:element name="AggregateShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="ormp_AggregateShares"/>
  <xs:element name="PercentageOfOutstandingShareCapital" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfOutstandingShareCapital"/>
  <xs:element name="PromissoryNote" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_PromissoryNote"/>
  <xs:element name="AdditionalPrincipalAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_AdditionalPrincipalAmount"/>
  <xs:element name="AnnumAndSecuredInterestPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AnnumAndSecuredInterestPercentage"/>
  <xs:element name="EquityCapitalizedAdjustedPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_EquityCapitalizedAdjustedPercentage"/>
  <xs:element name="OrdinarySharesClosingPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_OrdinarySharesClosingPercentage"/>
  <xs:element name="RevenueSharingPaymentPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RevenueSharingPaymentPercentage"/>
  <xs:element name="StockIssuedPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_StockIssuedPercentage"/>
  <xs:element name="AdjustedExercisePrice" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AdjustedExercisePrice"/>
  <xs:element name="ReversesplitAdjustedPricePerShare" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ReversesplitAdjustedPricePerShare"/>
  <xs:element name="ReversesplitAdjustedPrice" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ReversesplitAdjustedPrice"/>
  <xs:element name="AutomaticallyIncreasePercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AutomaticallyIncreasePercentage"/>
  <xs:element name="AnnualInterestPercentage" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AnnualInterestPercentage"/>
  <xs:element name="PercentageOfReWalkSales" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfReWalkSales"/>
  <xs:element name="ReverseStockSplitPerShare" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ReverseStockSplitPerShare"/>
  <xs:element name="ConsecutiveTradingDays" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ConsecutiveTradingDays"/>
  <xs:element name="PercentageOfLifewardOrdinaryShares" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PercentageOfLifewardOrdinaryShares"/>
  <xs:element name="FundedAmount" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="ormp_FundedAmount"/>
  <xs:element name="LimitedPartnersCommittedInvestment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="ormp_LimitedPartnersCommittedInvestment"/>
  <xs:element name="AgreementAxis" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:dimensionItem" id="ormp_AgreementAxis"/>
  <xs:element name="ALPHATauWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ALPHATauWarrantsMember"/>
  <xs:element name="AdditionalLoanAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AdditionalLoanAgreementMember"/>
  <xs:element name="AlphaTauMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_AlphaTauMember"/>
  <xs:element name="BioXcelMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_BioXcelMember"/>
  <xs:element name="BoardModifiedMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_BoardModifiedMember"/>
  <xs:element name="BuybackProgramMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_BuybackProgramMember"/>
  <xs:element name="ChiefScientificOfficerMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ChiefScientificOfficerMember"/>
  <xs:element name="ClinicalResearchOrganizationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ClinicalResearchOrganizationMember"/>
  <xs:element name="ClosingPennyWarrantMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ClosingPennyWarrantMember"/>
  <xs:element name="ConvertibleNoteMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ConvertibleNoteMember"/>
  <xs:element name="DNAMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_DNAMember"/>
  <xs:element name="ElevenEqualQuarterlyInstallmentsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ElevenEqualQuarterlyInstallmentsMember"/>
  <xs:element name="EmployeesAndDirectorsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_EmployeesAndDirectorsMember"/>
  <xs:element name="EnteraMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_EnteraMember"/>
  <xs:element name="EqualQuarterlyInstallmentsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_EqualQuarterlyInstallmentsMember"/>
  <xs:element name="ExUSProductRightsToGloperbaMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ExUSProductRightsToGloperbaMember"/>
  <xs:element name="ExercisePriceRangeOneMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ExercisePriceRangeOneMember"/>
  <xs:element name="ExercisePriceRangeThreeMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ExercisePriceRangeThreeMember"/>
  <xs:element name="ExercisePriceRangeTwoMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ExercisePriceRangeTwoMember"/>
  <xs:element name="ExtensionAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ExtensionAgreementMember"/>
  <xs:element name="FourEqualQuarterlyInstallmentsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_FourEqualQuarterlyInstallmentsMember"/>
  <xs:element name="FourMonthlyInstallmentsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_FourMonthlyInstallmentsMember"/>
  <xs:element name="GloperbaAndElyxybMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_GloperbaAndElyxybMember"/>
  <xs:element name="HapisgaMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_HapisgaMember"/>
  <xs:element name="InitialNotesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_InitialNotesMember"/>
  <xs:element name="InvestmentInAlphaTausSharesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_InvestmentInAlphaTausSharesMember"/>
  <xs:element name="InvestmentInAlphaTausWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_InvestmentInAlphaTausWarrantsMember"/>
  <xs:element name="IsraelDiscountBankLtdMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_IsraelDiscountBankLtdMember"/>
  <xs:element name="IsraelInnovationAuthorityMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_IsraelInnovationAuthorityMember"/>
  <xs:element name="KNRYMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_KNRYMember"/>
  <xs:element name="LicenseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_LicenseAgreementMember"/>
  <xs:element name="LidocaineTopicalSystemMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_LidocaineTopicalSystemMember"/>
  <xs:element name="LoanAgreementMeasuredInFairValueMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_LoanAgreementMeasuredInFairValueMember"/>
  <xs:element name="LoanAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_LoanAgreementMember"/>
  <xs:element name="LoanMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_LoanMember"/>
  <xs:element name="LoanToAnEquityMethodInvesteeMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_LoanToAnEquityMethodInvesteeMember"/>
  <xs:element name="MaturityDateMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_MaturityDateMember"/>
  <xs:element name="MeasurementInputCurveRateMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_MeasurementInputCurveRateMember"/>
  <xs:element name="MeasurementInputFloorRateMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_MeasurementInputFloorRateMember"/>
  <xs:element name="MeasurementInputYieldMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_MeasurementInputYieldMember"/>
  <xs:element name="MedicoxLicenseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_MedicoxLicenseAgreementMember"/>
  <xs:element name="MiriamKidronChiefScientificOfficerMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_MiriamKidronChiefScientificOfficerMember"/>
  <xs:element name="MiriamKidronMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_MiriamKidronMember"/>
  <xs:element name="NINAMedicalLtdMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NINAMedicalLtdMember"/>
  <xs:element name="NadavKidronPresidentAndChiefExecutiveOfficerMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NadavKidronPresidentAndChiefExecutiveOfficerMember"/>
  <xs:element name="NanoMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NanoMember"/>
  <xs:element name="NonEmployeesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NonEmployeesMember"/>
  <xs:element name="NotesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NotesMember"/>
  <xs:element name="NotesSecuritiesPurchaseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_NotesSecuritiesPurchaseAgreementMember"/>
  <xs:element name="OravaxMedicalIncMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_OravaxMedicalIncMember"/>
  <xs:element name="PelthosMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PelthosMember"/>
  <xs:element name="PennyWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PennyWarrantsMember"/>
  <xs:element name="PerformanceShareUnitsPSUsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PerformanceShareUnitsPSUsMember"/>
  <xs:element name="PreFundedWarrantsAndSharePurchaseWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PreFundedWarrantsAndSharePurchaseWarrantsMember"/>
  <xs:element name="PreFundedWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_PreFundedWarrantsMember"/>
  <xs:element name="ProfitSharingLoanAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ProfitSharingLoanAgreementMember"/>
  <xs:element name="RangeOfExercisePricesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RangeOfExercisePricesMember"/>
  <xs:element name="ResearchAndDevelopmentExpensesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ResearchAndDevelopmentExpensesMember"/>
  <xs:element name="RevaluationOfAlphaTauNetMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RevaluationOfAlphaTauNetMember"/>
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  <xs:element name="RevaluationOfHapisgaNetMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RevaluationOfHapisgaNetMember"/>
  <xs:element name="RevaluationOfOtherMarketableSecuritiesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RevaluationOfOtherMarketableSecuritiesMember"/>
  <xs:element name="RevaluationOfProfitSharingLoanAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RevaluationOfProfitSharingLoanAgreementMember"/>
  <xs:element name="RevaluationOfRoyaltyVestLoanNetMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RevaluationOfRoyaltyVestLoanNetMember"/>
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  <xs:element name="RoyaltyPurchaseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RoyaltyPurchaseAgreementMember"/>
  <xs:element name="RoyaltyPurchaseAgreementPaymentMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RoyaltyPurchaseAgreementPaymentMember"/>
  <xs:element name="RoyaltyVestMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RoyaltyVestMember"/>
  <xs:element name="RoyaltyVestSharesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RoyaltyVestSharesMember"/>
  <xs:element name="RoyaltyVestWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_RoyaltyVestWarrantsMember"/>
  <xs:element name="ScilexCommonStockMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScilexCommonStockMember"/>
  <xs:element name="ScilexHoldingCompanyMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScilexHoldingCompanyMember"/>
  <xs:element name="ScilexMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScilexMember"/>
  <xs:element name="ScilexTransactionMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScilexTransactionMember"/>
  <xs:element name="SharePurchaseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_SharePurchaseAgreementMember"/>
  <xs:element name="ShnidaMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ShnidaMember"/>
  <xs:element name="StockBlockATMAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_StockBlockATMAgreementMember"/>
  <xs:element name="SubsequentPennyWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_SubsequentPennyWarrantsMember"/>
  <xs:element name="ThreeEqualAnnualInstallmentsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ThreeEqualAnnualInstallmentsMember"/>
  <xs:element name="ThreeEqualQuarterlyInstallmentsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ThreeEqualQuarterlyInstallmentsMember"/>
  <xs:element name="TotalMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TotalMember"/>
  <xs:element name="TovaChochamaMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TovaChochamaMember"/>
  <xs:element name="TovaChochmaImNachalaLtdMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TovaChochmaImNachalaLtdMember"/>
  <xs:element name="TrancheAMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TrancheAMember"/>
  <xs:element name="TrancheANoteMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TrancheANoteMember"/>
  <xs:element name="TrancheBMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TrancheBMember"/>
  <xs:element name="TrancheBNoteConsentMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TrancheBNoteConsentMember"/>
  <xs:element name="TrancheBNoteMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TrancheBNoteMember"/>
  <xs:element name="TrancheBWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TrancheBWarrantsMember"/>
  <xs:element name="TwoThousandTwentyThreeScilexTransactionMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TwoThousandTwentyThreeScilexTransactionMember"/>
  <xs:element name="TwoZeroOneNinePlanMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_TwoZeroOneNinePlanMember"/>
  <xs:element name="WarrantsNoteBMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_WarrantsNoteBMember"/>
  <xs:element name="ZTlidoLicenseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ZTlidoLicenseAgreementMember"/>
  <xs:element name="securitiesPurchaseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_securitiesPurchaseAgreementMember"/>
  <xs:element name="ConvertibleSecuredPromissoryNoteLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ConvertibleSecuredPromissoryNoteLineItems"/>
  <xs:element name="OtherNonMarketableEquitySecuritiesAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_OtherNonMarketableEquitySecuritiesAbstract"/>
  <xs:element name="ScheduleOfIncomeLossBeforeTaxesOnIncomeAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="ormp_ScheduleOfIncomeLossBeforeTaxesOnIncomeAbstract"/>
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</xs:schema>
